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Babu S, Nicholson KA, Rothstein JD, Swenson A, Sampognaro PJ, Pant P, Macklin EA, Spruill S, Paganoni S, Gendron TF, Prudencio M, Petrucelli L, Nix D, Landrette S, Nkrumah E, Fandrick K, Edwards J, Young PR. Apilimod dimesylate in C9orf72 amyotrophic lateral sclerosis: a randomized phase 2a clinical trial. Brain. 2024 Sep 3;147(9):2998-3008. https://pubmed.ncbi.nlm.nih.gov/38606777/
Sampognaro PJ, Arya S, Knudsen GM, et al. Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases. Mol Neurodegener. 2023;18(1):29. https://pubmed.ncbi.nlm.nih.gov/37131250/
Swetha Mohan, Paul J. Sampognaro, Andrea R. Argouarch, Jason C. Maynard, Anand Patwardhan, Emma C. Courtney, Amanda Mason, Kathy H. Li, William W. Seeley, Bruce L. Miller, Alma Burlingame, Mathew P. Jacobson, Aimee Kao. Processing of progranulin into granulins involves multiple lysosomal proteases and is affected in frontotemporal lobar degeneration. Mol. Neurodegeneration. 16, 51 (2021) https://pubmed.ncbi.nlm.nih.gov/34344440/
Sushmitha Gururaj, Paul J. Sampognaro, Andrea R. Argouarch and Aimee W. Kao. Progranulin Adsorbs to Polypropylene Tubes and Disrupts Functional Assays: Implications for Research, Biomarker Studies, and Therapeutics. Frontiers in Neuroscience. 2020 Dec 14;14:602235. https://pubmed.ncbi.nlm.nih.gov/33381010/
Sloan EA, Sampognaro PJ, Junn JC, Chin C, Jacques L, Ramachandran PS, DeRisi JL, Wilson MR, Kriegstein AR, Bollen AW, Solomon DA, Margeta M, Engstrom JW. Neuroglial stem cell-derived inflammatory pseudotumor (n-SCIPT): clinicopathologic characterization of a novel lesion of the lumbosacral spinal cord and nerve roots following intrathecal allogeneic stem cell intervention. Acta Neuropathol. 2019 Dec;138(6):1103-1106. https://pubmed.ncbi.nlm.nih.gov/31659431
Sampognaro PJ, Vatsavayai SC, Cosme CG, Hwang JL, Nolan A, Huang EJ, Seeley WW, De May MG. C9orf72-specific phenomena associated with frontotemporal dementia and gastrointestinal symptoms in the absence of TDP-43 aggregation. Acta Neuropathol. 2019 Dec;138(6):1093-1097. https://pubmed.ncbi.nlm.nih.gov/31624869/
Clifford MA, Athar W, Leonard CE, Russo A, Sampognaro PJ, Van der Goes MS, Burton DA, Zhao X, Lalchandani RR, Sahin M, Vicini S, Donoghue MJ. EphA7 signaling guides cortical dendritic development and spine maturation. Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4994-9. https://pubmed.ncbi.nlm.nih.gov/24707048/
Bricceno KV, Sampognaro PJ, Van Meerbeke JP, Sumner CJ, Fischbeck KH, Burnett BG. Histone deacetylase inhibition suppresses myogenin-dependent atrogene activation in spinal muscular atrophy mice. Human Molecular Genetics. October 2012; 21: 4448-59. https://pubmed.ncbi.nlm.nih.gov/24707048
